UniProt

Returns one ARBA rule - a machine-learned annotation rule - with its condition set (InterPro signatures, taxon) and the annotations it confers.

Searches the ARBA machine-learned rule set and returns matching rules with their conditions and conferred annotations.

Returns one literature record as UniProt holds it: title, authors or authoring group, journal, volume and pages, publication date, abstract where available, and PubMed and DOI cross-references.

Searches the literature UniProt cites and returns matching references with titles, authors, journals and PubMed and DOI identifiers.

Returns the registry record for one database UniProt links out to: its full name, abbreviation, category, home server, the URL template used to build entry links, its reference publication and how many UniProt entries cross-reference it.

Returns every database that can be used as a cross-reference filter in a UniProtKB query, grouped by category with the short value each one is named by.

Searches the registry of databases UniProt cross-references and returns matching records with their categories, link templates and entry counts.

Returns one entry from UniProt's human disease vocabulary: name, acronym, definition, alternative names, keyword and MIM cross-references and the count of proteins annotated with it.

Searches UniProt's human disease vocabulary and returns matching diseases with definitions, acronyms and cross-references.

Returns full UniProtKB records for up to 1000 accessions named in one request, in a single results array.

Returns the complete UniProtKB record for one accession: protein and gene names, organism and lineage, the amino-acid sequence, function and subunit comments, sequence features such as domains, binding sites and variants, GO terms, keywords, literature references and every database cross-reference.

Returns every publication UniProt associates with one accession - both the curated references in the entry and additional computationally mapped and community-submitted papers - with authors, title, journal, PubMed and DOI identifiers and the annotation categories each paper supports.

Returns the evidence codes UniProt annotations can carry, grouped into manual, automatic and experimental assertions, each with its name and code.

Returns the gene-centric view for one accession within its proteome: the canonical protein with its sequence, and the related isoform and paralogous entries grouped under the same gene.

Searches the gene-centric view and returns one record per gene with its canonical protein and related entries, across proteomes.

Returns one UniProt help or documentation article as structured JSON: id, title, categories, last-modified date and the full Markdown body.

Searches UniProt's help and documentation and returns matching articles with their ids, titles, categories and highlighted match snippets.

Returns one controlled-vocabulary keyword: its name, definition, category, parent and child terms, synonyms, GO mappings and how many reviewed and unreviewed entries carry it.

Searches the UniProt keyword vocabulary and returns matching keywords with definitions, categories and hierarchy.

Returns one proteome record: the organism and its taxonomy, the source genome assembly and annotation, whether it is a reference or redundant proteome, its BUSCO and CPD completeness scores, protein counts and the component chromosomes and plasmids.

Searches the proteome collection and returns matching proteomes with organism, taxonomy, type, completeness scores and protein counts.

Returns the full text of one UniProt or Swiss-Prot release note, with its release date and the complete change narrative for that release.

Searches UniProt release notes and returns matching notes with their ids, titles, release dates and highlighted match snippets.

Returns the catalogue of field names that a dataset's endpoints accept in the fields parameter, grouped by section, each with its human label and sortable flag.

Runs a UniProt query against the whole knowledgebase and returns the matching entries as full records, with the total match count in the x-total-results header and a cursor for the next page.

Returns only the facet breakdown for a query - counts per review status, model organism, protein existence, annotation score, length band and so on - with no entry bodies, because the page size is pinned to zero.

Returns the query fields a dataset's search endpoint accepts, each with its term name, data type, example value and the validation regex the upstream applies.

Returns one term from UniProt's subcellular location vocabulary: name, definition, synonyms, category, GO mapping, parent and child terms and the counts of entries annotated with it.

Searches the subcellular location vocabulary and returns matching terms with definitions, categories and GO mappings.

Returns up to 1000 taxonomy nodes named in one request, in a single results array.

Returns one node of the UniProt taxonomy: scientific and common names, mnemonic, rank, parent, synonyms, lineage links and the counts of UniProtKB entries and proteomes attached to it.

Searches the UniProt taxonomy by name and returns the matching nodes with their IDs, ranks, parents and synonyms.

Returns the single UniParc record UniProt considers the best representative for the given input - the longest reviewed UniProtKB sequence among the matching archive entries - rather than the whole matching set.

Returns the single UniParc record whose sequence corresponds to a given UniProtKB accession, with all of that sequence's cross-references across source databases.

Returns the UniParc records cross-referenced by an identifier from any source database - EMBL, RefSeq, Ensembl, PDB, a patent office and so on - letting you resolve a foreign ID to a UniParc sequence.

Returns just the cross-reference list of one UniParc record, paged: source database, identifier, version, gene and protein name, organism, creation and update dates and whether the reference is still active.

Returns UniParc records for up to 1000 UPIs named in one request, in a single results array.

Returns one UniParc record: the non-redundant protein sequence, its CRC64 and MD5 checksums, and every database cross-reference that has ever carried that exact sequence, with the source database, identifier, version, organism and active flag.

Searches the UniParc sequence archive and returns matching records with their UPI, sequence, cross-reference count and common taxa.

Returns one UniRef cluster: its identity threshold, member count, common taxon, seed, representative member with its sequence, and the member list with organisms and accessions.

Returns the member list of one UniRef cluster, paged: each member's accession or UniParc ID, protein name, organism, taxon ID, sequence length and whether it is the seed.

Searches the UniRef clusters and returns matching clusters with their identity level, size, common taxon and representative member.

Returns one curator-written UniRule: the condition sets a sequence must satisfy (InterPro signatures, taxonomy, sequence length and so on) and the annotations the rule then applies, plus its template entries and how many proteins it hits.

Searches the UniRule rule set and returns matching rules with their conditions, applied annotations and statistics.

Returns a line-by-line diff between two versions of the same UniProtKB entry, with the full flat-file text of both versions and the changed lines marked.

Returns the UniSave version history of one accession: every entry version with its sequence version, entry name, database (Swiss-Prot or TrEMBL) and the release in which it first and last appeared.